富士化学有限公司是一个的专业硅胶填料制造商，拥有70多年的历史，积累了丰富的经验。硅胶产品始终是其核心业务，在中国大陆拥有广泛的工业客户基础，以其优越的性价比，是国内天然药物和合成药等原料药生产商的首选填料之一。
Fuji(富士)填料 CHROMATOREX Amino Silica Gel
A multi-purpose chromatography support
Introduction
LIQUID CHROMATOGRAPHY (LC) is a useful technique in purifying organic and natural compounds in laboratories and industrial production. Especially normal phase chromatography using silica gel and non-polar solvent is a popular choice because of high solubility of compounds and easy post-treatment. However, there is a difficulty to separate basic compounds such as alkaloids and nitrogen-containing compounds due to ionic interaction between silica gel and solutes. These alkaloids have superior efficacy in pharmaceutical fields both natural and synthesis products.
Fuji Silysia Chemical Ltd. (FSC), a manufacturer of large amounts of silica gel (CHROMATOREX) for LC since the last 40 years, has developed amino-propyl bonded silica, which can be used in various application techniques:
- Normal phase LC for basic compounds like alkaloids
- Reversed phase LC for vitamins or sugars application
- Metal scavenger removal/recovery for acid chlorides, isocyanates,..
- Precursor to develop chromatography chiral packings
The CHROMATOREX amino-propyl bonded silica can be seen as a multi-purpose chromatography support.
Chromatorex Surface Characteristics
FSC introduces 3 major grades to cover a large field of applications:
-Applications-
- NH MB100-75/200 Open column
- NH MB100-40/75 Flash column, Cartridge column
- NH SMB100-20/45 Cartridge column, HPLC
Of course due to the availability of a large range of bare silica manufactured by FSC, FSC is able to provide additional product suitable for a particular application.
These grades resulted from silica surface treatment where the silanol groups react with the amino-propyl silane by chemical bonding:
