Specifications
CAS # : 127-33-3
Molecular Formula : C21H21ClN2O8
Molecular Weight : 468.9
Source : Streptomyces sp.
Appearance : Yellow to orange solid
Purity : >98% by HPLC
Long Term Storage : -20°C
Solubility : Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Application Notes
Demeclocycline, a chlortetracycline analogue produced by a mutagenised strain of Streptomyces aureofaciens, was 
first isolated in 1957. Like all tetracyclines, demeclocycline shows broad spectrum antibacterial and antiprotozoan 
activity and acts by binding to the 30S and 50S ribosomal subunits, blocking protein synthesis. Demeclocycline has 
been extensively cited in the literature with over 800 references relating almost exclusively to in vivo use.