Specifications
CAS # : 873857-62-6
Molecular Formula : C52H74Cl2O18
Molecular Weight : 1058.0
Source : Dactylosporum aurantiacum
Appearance : White solid
Purity : >98% by HPLC
Long Term Storage : -20°C
Solubility : Soluble in ethanol, methanol, DMF or DMSO. Limited water solubility.
Application Notes
Fidaxomicin is a recently marketed antibiotic with a confusing history dating back to its original isolation in 1975.
Fidaxomicin is the major analogue of a family of macrocyclic lactones, isolated independently by three different
groups from cultures belonging to three different genera (Actinoplanes, Dactylosporangium and Micromonospora)
known as lipiarmycin A3, tiacumicin B and clostomicin B1, respectively. Fidaxomicin is a narrow spectrum antibiotic
with excellent activity against Gram positive bacteria, notably Clostridium difficile. Fidaxomicin acts in the
gastrointestinal tract without undue disruption to gut microbial flora.
