Specifications
CAS # : 87810-56-8
Molecular Formula : C19H26O9P
Molecular Weight : 452.4
Source : Streptomyces sp.
Appearance : White powder
Purity : >95% by HPLC
Long Term Storage : -20°C
Solubility : Soluble in water, optimial stability in aqueous buffered solutions at pH 6.5.
NOTE: hydrolysis of the phosphate ester will result from inappropriate
storage.
Application Notes
Fostriecin is the most fully characterised member of a family of phosphate esters of a triene antibiotic. The
antitumour potential of fostriecin has attracted considerable interest, focused on its mode of action as a
topoisomerase II inhibitor. Subsequent research has focused on this metabolite's selective inhibition of protein
phosphatase PP2A.
