Specifications
CAS # : 57749-43-6
Molecular Formula : C22H31NO4
Molecular Weight : 373.5
Source : Fusarium equiseti
Appearance : Light tan to tan solid
Purity : >99% by HPLC
Long Term Storage : -20°C
Solubility : Soluble in DMF or DMSO. Moderately soluble in methanol or ethanol. Poor
water solubility.
Application Notes
The tetramic acid, equisetin, is produced by a number of species of Fusarium. Interest in equisetin emerged with
reports of its inhibitory activity against HIV-1 integrase in vitro that was mechanistically distinct from previously
described inhibitors. Equisetin inhibits 3' end-processing and strand transfer, as well as disintegration catalysed by
either the full-length enzyme or the truncated integrase core.