Cytisine also called Sparteine,ulexine.so far, this product is extracted from the Sophora alopecuroides seeds . But the seeds of the Golden Acacia tree and Eagle caught beans, wild cassia, clover leaves Huanghua and other plants can also extract Cytisine .

在西北尤其是新疆地区广泛分布。Sophora alopecuroides is widely distributed in Northwest China and Xinjiang .

早在上世纪50年代初，保加利亚药学工作者一经发现，欧洲栽种的观赏花金合欢树可以提取出金雀花碱，试验证实这种生物碱具有良好的戒烟作用。

As early as the early 1950s, Bulgarian pharmacy workers once discovered that the European planted ornamental flower acacia tree can be extracted from the Cytisine, the test confirmed that this alkaloid has a good smoking cessation.

1964年保加利亚在世界上率先推出以金雀花碱为主要成分的植物戒烟药-Tabex(每片含金雀花碱1.5mg).该产品迅速风靡整个东欧地区及前苏联各加盟共和国。

In 1964 Bulgaria in the world took the lead in the introduction of Cytisine as the main component of the plant smoking cessation drug - Tabex (each containing gold carnate 1.5mg). The product quickly swept the entire Eastern Europe and the former Soviet Union joined the Republic.

据报道，我国港台地区也在销售金雀花碱这种天然戒烟产品。目前一个疗程（25天）的Tabex 所需的费用大约在5-15美元，相比市场上的畅销戒烟产品Nicolette ,一个疗程至少需要100美元，但由于此产品是由东欧国家及前苏联研究，该产品至今未传入美，西欧（德国市场除外），其理由是该产品未做过正规药理实验和各种药代动力学实验及长期毒性实验，所以，英，美，法，日本，澳大利亚，加拿大至今未批准金雀花碱制剂作为植物戒烟药在其国内上市。

It is reported that HongKong,China  and Taiwan region is also selling the Cytisine this natural smoking cessation products. At present, a course of treatment (25 days) Tabex cost about $ 5-15, compared to the market's best-selling smoking products Nicolette, a course of at least $ 100,  because this product is the Eastern European countries and the former Soviet Union research, The product has not been introduced to the United States, Western Europe (except the German market), the reason is that the product has not done a regular pharmacological experiments and a variety of pharmacokinetic experiments and long-term toxicity experiments, so, Britain, the United States, France, , Canada has not approved cytisine preparations as a plant smoking cessation drug in its domestic market.

据报道i，英国一些研究机构已经开展金雀花碱安全性研究，其价格低廉且确实有很好的戒烟效果。

It is reported that some research institutions in the UK have conducted a study on the safety of genus sanguinine, which is cheap and does have a good effect of smoking cessation.

为什么金雀花碱具有戒烟效果why Cytisine has a smoking cessation effect ?

近年来西方国家研究人员做了大量的研究工作，据美国（Drug、Alcohol Depen）2008年一月报道，金雀花碱可作为一种有效的戒烟药使用，因为它的化学结构与尼古丁的化学机构非常相似，所以进入脑内后可竞争性的与尼古丁受体结合。同时，与台湾一个出名的戒烟产品（chantix）非常相似，而且药理研究证实，金雀花碱属于尼古丁乙酰胆碱受体的部分拮抗剂。而且金雀花碱与α-4β-2 受体的亲和力比现有各种戒烟效果更大一些，，在上个世纪70年代，德国已有机构做过金雀花碱人体安全性试验并得出结论：以现有Tabex 的剂量，该产品长期服用，非常安全。近年来欧洲一些保健品厂家已经陆续开发出金雀花碱的含片，鼻喷雾剂，咀嚼片，口香糖和透皮释放剂，多重不同类型的戒烟产品。

In recent years, researchers in Western countries have done a lot of research work, according to the United States (Drug, Alcohol Depen) reported in January 2008, Cytisine can be used as an effective smoking cessation because of its chemical structure and nicotine chemistry Institutions are very similar, so enter the brain after the competitive combination with the nicotine receptor. At the same time, it is very similar to a well-known chanting product in Taiwan, and pharmacological studies have confirmed that Cytisine is part of the antagonist of nicotine acetylcholine receptors. And the affinity of the genistine with the α-4β-2 receptor is greater than that of the existing effects of smoking cessation. In the 1970s, the German body had done a human body safety test and had Conclusion: With the current Tabex dose, the product is taken for a long time and is very safe. In recent years, some European health care products manufacturers have gradually developed a hot pack of spikes, nasal spray, chewable tablets, chewing gum and transdermal release agent, multiple different types of smoking cessation products.

药理作用 Pharmacological effects

可生产戒烟药，急救药和止咳药

It Can produce smoking cessation drugs, emergency medicine and cough medicine

临床用金雀花碱0. 15%水溶液供肌肉或静脉注射，抢救因手术和各种创伤引起的反射性呼吸暂停、休克和新生儿窒息等。近期研究表明，该类生物碱还具有抗心率失常、抗微生物感染、抗溃疡、升高白细胞等多方面的药理作用，特别是该类化合物较强的抗癌活性。

Clinical use of Cytisine 0. 15% aqueous solution for muscle or intravenous injection, rescue due to surgery and various trauma caused by reflex apnea, shock and neonatal asphyxia. Recent studies have shown that such alkaloids also have anti-heart rate disorders, anti-microbial infection, anti-ulcer, elevated white blood cells and other aspects of pharmacological effects, especially the strong anticancer activity of such compounds.

安全术语( Safety terms)

S26In case of contact with eyes, rinse immediately with plenty of water and seek medical advice.

不慎与眼睛接触后，请立即用大量清水冲洗并征求医生意见。

 S28After contact with skin, wash immediately with plenty of soap-suds.

 不慎与皮肤接触后，立即用大量肥皂水冲洗。

 S36/37Wear suitable protective clothing and gloves.

穿戴适当的防护服和手套。

S45In case of accident or if you feel unwell, seek medical advice immediately (show the label whenever possible.)

若发生事故或感不适，立即就医(可能的话，出示其标签)。